This expert discussion critically analyzed the evolving landscape of misinformation, focusing on the role of deepfakes and AI-driven content. The panel discussed a rigorous, evidence-based discussion with diverse academic insights from psychology, communications, public policy, and political science. Topics included trends in misinformation, the effectiveness of mitigation strategies like fact-checking and media literacy, the impact of foreign influence operations, and what we know or don't know yet based on the most up-to-date academic literature. Given the focus of the AAAIP on providing non-partisan evidence to inform policy, the conversation also highlighted actionable policy recommendations for addressing these challenges.